MANAGEMENT & ADVISERS
Zhijian Lu, Ph.D. , CEO
Expert organic synthetic and medicinal chemist. Experienced in the development and synthesis
of small molecules with characteristics with tractability as medicines. Record at Merck includes
leading role that synthesized molecules that went into Phase III. Additional expertise in
automated synthesis and purification and Six Sigma processes.
Alison M. Strack, Ph.D., CSO
Experienced neuroscientist and drug discovery expert. Led multiple cross-functional programs
in obesity, diabetes and cardiovascular from early discovery to Phase II while at Merck Research
Xibin Liao, Ph.D., General Manager
Expert medicinal chemist in the development and synthesis of small molecules with
characteristics with tractability as medicines. Track record at Merck includes synthesis of small
molecules for two programs that went into clinical development.
Expertise in GPCRs and in vitro pharmacology. Part of teams advancing compounds into
Scientific Advisory Board
Dr. James Balkovec: organic and
Dr. Philippe Durette: patent law
Prof. Jef DeBrabander: cancer and
Prof. Spencer Knapp: organic
chemistry/natural product synthesis
Prof. Jeff Toney: metabolic disease,
Prof. Zhong-Yin Zhang:
Experience that matters
Demonstrated Quality, Speed, and Value
The company has a group of experts with combined decades of experience in drug discovery.
Medicinal Chemistry: experienced experts in drug discovery processes; key roles in delivery of
compounds to the market (Cancidas®) and clinical trials (PhIII CETP Inhibitor Anacetrapib).
Biology and Pharmacology: experienced team with expertise in diabetes, obesity, cardiovascular
diseases and neuroscience. Previous lead roles in bringing multiple compounds in the area of
metabolic disorders into clinical trials. Capabilities include in vivo biology, cell and molecular biology,
enzymology, GPCRs, and translational medicine.